Perturbed adipose tissue hydrogen peroxide metabolism in centrally obese men: Association with insulin resistance.

May G AklEman FawzyMaha DeifAyman FaroukAmany K Elshorbagy

Published in: PloS one (2017)

These findings suggest that adipose tissue catalase shows compensatory up-regulation in response to obesity-induced H2O2 accumulation, and that perturbed H2O2 metabolism in visceral fat is linked to insulin resistance in obese humans.

Keyphrases

adipose tissue
insulin resistance
hydrogen peroxide
high fat diet
high fat diet induced
nitric oxide
polycystic ovary syndrome
high glucose
metabolic syndrome
diabetic rats
weight loss
glycemic control
middle aged
skeletal muscle
endothelial cells
physical activity
body mass index
obese patients
stress induced