Factors associated with weight loss in people with overweight or obesity living with type 2 diabetes mellitus: Insights from the global DISCOVER study.
Vittal HejjajiJuan J Gorgojo-MartinezFengming TangJulia Blanco GarneloAndrew CooperJesús MedinaMiren Sequera MutiozabalKamlesh Khunti F MedSciAntonio NicolucciMarina V ShestakovaLi-Nong JiMarília Brito GomesHirotaka WatadaJiten VoraAli O MalikMikhail KosiborodSuzanne V ArnoldPublished in: Diabetes, obesity & metabolism (2022)
In this large contemporary prospective study, approximately one in five participants with early-stage type 2 diabetes and overweight/obesity lost ≥5% weight over 3 years. The type of GLM has the most impact on weight loss over time, highlighting the need for a careful selection of agents that takes baseline weight into consideration.