The effect of anti-CTLA4 treatment on peripheral and intra-tumoral T cells in patients with hepatocellular carcinoma.

David AgdashianMei ElGindiChangqing XieMilan SandhuDrew PrattDavid E KleinerWilliam D FiggJulie A RytlewskiCatherine SandersErik C YuskoBradford WoodDavid VenzonGagandeep BrarAustin G DuffyTim F GretenFirouzeh Korangy

Published in: Cancer immunology, immunotherapy : CII (2019)

In summary, we observed a clear activation of T cell responses in HCC patients treated with tremelimumab and identified potential biomarkers which will help identify patients responding to immunotherapy with anti-CTLA4.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
peritoneal dialysis
prognostic factors
patient reported outcomes