Novel Single Inhibitor of HDAC6/8 and Dual Inhibitor of PI3K/HDAC6 as Potential Alternative Treatments for Prostate Cancer.

Fabiana Sélos GuerraDaniel Alencar Rodrigues Carlos Alberto Manssour Fraga Patricia Dias Fernandes

Published in: Pharmaceuticals (Basel, Switzerland) (2021)

LASSBio-1911 and LASSBio-2208 demonstrated significant activity in reducing cell viability and migration. These compounds can be further used as prototypes for the development of new potential anticancer alternative treatments.

Keyphrases

prostate cancer
radical prostatectomy
histone deacetylase
human health
climate change