Utility and limitations of patient-adjusted D-dimer cut-off levels for diagnosis of venous thromboembolism - A systematic review and meta-analysis.

This study indicates that adjustment of D-dimer thresholds to patient-specific factors is safe and embodies considerable potential for reduction of imaging. However, robustness, safety, and efficiency vary considerably between different adjustment strategies with a high degree of heterogeneity. This article is protected by copyright. All rights reserved.