Gene Interaction Network Analysis Reveals IFI44L as a Drug Target in Rheumatoid Arthritis and Periodontitis.

Pradeep Kumar YadalamThilagar SivasankariSanthiya RengarajMaryam Hassan Mugri Mohammed E Sayed Sameer Saeed KhanMona Awad KamilShilpa BhandiA Thirumal Raj Shankaragouda Patil Artak Heboyan

Published in: Molecules (Basel, Switzerland) (2022)

The identified IFI44L may represent a common drug target for periodontitis and rheumatoid arthritis. Vemurafenib could be a potent anti-inflammatory drug for both diseases.

Keyphrases

rheumatoid arthritis
network analysis
anti inflammatory
disease activity
adverse drug
ankylosing spondylitis
interstitial lung disease
drug induced
gene expression
emergency department
idiopathic pulmonary fibrosis