Biochemical and molecular study on interleukin-1β gene expression and relation of single nucleotide polymorphism in promoter region with Type 2 diabetes mellitus.

Safaa I TayelEman A M FoudaElsayed I ElshayebAsmaa R A EldakamawySalah M El-Kousy

Published in: Journal of cellular biochemistry (2018)

C allele of IL-1 β -511 T >C could be considered risk factor contributor to T2DM and excess level of IL-1 β transcript may disclose to some degree the inflammatory role of cytokines in T2DM.

Keyphrases

gene expression
dna methylation
risk factors
oxidative stress
transcription factor
glycemic control
type diabetes
adipose tissue
single molecule
insulin resistance