Macrophage Nrf 2 the rescue.

Published in: The Journal of cell biology (2023)

The exuberant phagocytosis of apoptotic cell corpses by macrophages in Drosophila embryos creates highly oxidative environments. Stow and Sweet discuss work from Clemente and Weavers (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202203062) showing for the first time how macrophage Nrf2 is primed to help sustain immune function and mitigate bystander oxidative damage.

Keyphrases

single cell
oxidative stress
cell therapy
adipose tissue
cell death
stem cells
anti inflammatory