Laboratory diagnosis of heparin-induced thrombocytopenia: A retrospective experience.
Agathe HerbMathilde DepierreuxJordan WimmerDelphine RollandMartine TebacherAude LambertChayma LadhariMircea CristinarXavier DelabrancheThierry KrummelDominique PayaMaleka SchenckLaurent MauvieuxLaurent SattlerPublished in: Journal of clinical laboratory analysis (2023)
This study shows that ELISA can rule out HIT with an excellent NPV, especially when combined with the 4T risk score. Nonetheless, it has low specificity; hence, it needs to be associated with a functional assay.