Orbicularis Oculi Muscle Immunohistochemical, Metabolic, and Morphometric Differences in Affected and Nonaffected Sides in Hemifacial Spasm vs Healthy Subjects.
Tammy Hentona OsakiGustavo R GameiroMidori H OsakiTeissy OsakiEliene D CamposRubens BelfortSuely K N MariePublished in: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society (2022)
This study's findings suggest that repeated contractions might lead to OOM fiber hypertrophy, increased mitochondrial metabolism, and possible conversion of fast-twitch orbicularis oculi muscle fibers into slow-twitch fibers in patients with HFS. Alterations were observed in affected and nonaffected sides, confirming initial findings that the nonaffected side is not normal in this unique condition.
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