Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1-ZEB1 Axis-Mediated Epithelial-Mesenchymal Transition.

Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

Published in: Molecular cancer research : MCR (2024)

These findings uncover a novel regulatory role of HTR2B signaling on colorectal cancer metastasis, which provide experimental evidences for potential HTR2B-targeted anti-colorectal cancer metastasis therapy.

Keyphrases

epithelial mesenchymal transition
transforming growth factor
signaling pathway
long non coding rna
stem cells
transcription factor
human health
bone marrow