Cell-free DNA analysis for recurrent respiratory papillomatosis: A case report.
Satoshi YamadaKotaro KanoRyuji IshikawaAtsushi ImaiDaiki MochizukiKotaro MoritaKazutaka TakeuchiYoshinori TakizawaHideya KawasakiKiyoshi MisawaPublished in: Clinical case reports (2024)
A 35-year-old male presented with recurrent respiratory papillomatosis. Human papillomavirus type 11 was detected from all sites of tumor tissue DNA by PCR. The pre-surgery cell-free DNA (cfDNA) viral load (3.33 × 10 3 copies/ng DNA) fell below the post-surgical detection limits on achieving remission, suggesting cfDNA's potential as a biomarker.