Beneficial Effects of Glucagon-Like Peptide-1 (GLP-1) in Diabetes-Induced Retinal Abnormalities: Involvement of Oxidative Stress.
Hugo RamosPatricia BogdanovJoel SampedroJordi HuertaRafael SimòCristina HernandezPublished in: Antioxidants (Basel, Switzerland) (2020)
GLP-1 modulates the antioxidant defense system in the diabetic retina and has a neuroprotective action favoring DNA repair and neuron cells proliferation.
Keyphrases
- dna repair
- oxidative stress
- induced apoptosis
- dna damage
- diabetic rats
- type diabetes
- diabetic retinopathy
- signaling pathway
- optic nerve
- cardiovascular disease
- dna damage response
- optical coherence tomography
- cell cycle arrest
- high glucose
- endoplasmic reticulum stress
- ischemia reperfusion injury
- glycemic control
- wound healing
- drug induced
- endothelial cells
- brain injury
- metabolic syndrome
- heat shock
- cell proliferation
- skeletal muscle
- blood brain barrier
- insulin resistance
- stress induced