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Androgen receptor DNA methylation is an independent determinant of glucose metabolic disorders in women; testosterone plays a moderating effect.

Xue LiuWenqian HuoRui ZhangDandan WeiRunqi TuZhicheng LuoYan WangXiaokang DongDou QiaoPengling LiuLi ZhangKeliang FanLuting NieXiaotian LiuLinlin LiChongjian WangZhenxing Mao
Published in: Journal of diabetes (2020)
Our findings demonstrate that ARm was positively associated with IFG in women and the associations would be weakened by testosterone. The individuals experiencing low testosterone and ARm levels reported a lower state of IFG than those who experienced high levels of testosterone and ARm in women.
Keyphrases
  • replacement therapy
  • polycystic ovary syndrome
  • dna methylation
  • pregnancy outcomes
  • cervical cancer screening
  • breast cancer risk
  • gene expression
  • genome wide
  • type diabetes
  • pregnant women
  • blood glucose
  • weight loss