Breathable and Stretchable Dressings for Accelerating Healing of Infected Wounds.
Le WangWenfu ZhengQinghong HouLeni ZhongQizhen LiXingyu JiangPublished in: Advanced healthcare materials (2022)
Multidrug-resistant (MDR) bacteria-infected wounds are challenging issues that threaten human health. Herein, L-thioproline (T) and Boc-capped L-thioproline (BT)-decorated gold nanoparticles (TBT-GNPs) with potent antibacterial activity against MDR bacteria are reported. The TBT-GNPs are composited with bacterial cellulose to form wound dressings which show excellent antimicrobial performance both in vitro and in vivo. Moreover, this dressing is both breathable and stretchable which is favorable for gas exchange to accelerate the wound healing. This work is insightful for developing multifunctional dressings to satisfy the clinical requirements.
Keyphrases
- wound healing
- multidrug resistant
- human health
- gold nanoparticles
- risk assessment
- drug resistant
- gram negative
- acinetobacter baumannii
- reduced graphene oxide
- klebsiella pneumoniae
- climate change
- staphylococcus aureus
- drug delivery
- silver nanoparticles
- room temperature
- ionic liquid
- cancer therapy
- quantum dots
- cystic fibrosis