Antenatal magnesium sulphate and adverse neonatal outcomes: A systematic review and meta-analysis.

Emily Shepherd Rehana A SalamDeepak ManhasAnne R SynnesPhilippa MiddletonMaria Makrides Caroline A Crowther

Published in: PLoS medicine (2019)

Our findings do not support clear associations between antenatal magnesium sulphate for beneficial indications and adverse neonatal outcomes. Further large, high-quality studies (prospective cohorts or individual participant data meta-analyses) assessing specific outcomes, or the impact of regimen, pregnancy, or birth characteristics on these outcomes, would further inform safety recommendations. PROSPERO: CRD42013004451.

Keyphrases

pregnant women
preterm birth
systematic review
meta analyses
emergency department
type diabetes
machine learning
metabolic syndrome
adipose tissue
skeletal muscle
big data
weight loss
deep learning
adverse drug