Association between eNOS rs1799983 polymorphism and hypertension: a meta-analysis involving 14,185 cases and 13,407 controls.

Jikang ShiSiyu LiuYanbo GuoSainan LiuJiayi XuLingfeng PanYueyang HuYawen LiuYi Cheng

Published in: BMC cardiovascular disorders (2021)

We found that eNOS rs1799983 polymorphism is associated with the increased risk of hypertension under any genetic model. Moreover, investigations of gene-gene and gene-environment interactions are needed to give more insight into the association between eNOS rs1799983 polymorphism and hypertension.

Keyphrases

blood pressure
genome wide
copy number
endothelial cells
nitric oxide synthase
pi k akt
genome wide identification
nitric oxide
dna methylation
signaling pathway
arterial hypertension
transcription factor