Canine and feline uveal melanocytic tumours: Histologic and immunohistochemical characteristics of 32 cases.

Matheus Vilardo Lóes Moreira Ingeborg Maria LangohrMarina Rios de Araújo CamposEnio FerreiraBárbara CarvalhoGuilherme Reis BlumeFabiano Montiani-FerreiraRoselene Ecco

Published in: Veterinary medicine and science (2022)

Uveal melanocytomas were more common in dogs, and uveal melanomas were more frequent in cats. Anisocytosis, percentage of neoplastic cells with melanin, and mitotic count are important histologic characteristics of malignancy to evaluate in uveal melanocytic neoplasms. The proliferation and apoptotic indices are relevant when comparing malignant tumours with benign tumours.

Keyphrases

induced apoptosis
cell death
signaling pathway
cell cycle arrest
cell cycle
oxidative stress
peripheral blood