No-Reflow after PPCI-A Predictor of Short-Term Outcomes in STEMI Patients.
Larisa Renata Pantea-RoșanVlad Alin PanteaSimona Gabriela BungauDelia Mirela ŢițTapan BehlCosmin Mihai VesaCristiana BusteaRadu Dumitru MoleriuMarius RusMircea Ioachim PopescuVladiana-Romina TuriCamelia Cristina DiaconuPublished in: Journal of clinical medicine (2020)
The no-reflow phenomenon following primary percutaneous coronary intervention (PPCI) in acute ST-elevation myocardial infarction (STEMI) patients is a predictor of unfavorable prognosis. Patients with no-reflow have many complications during admission, and it is considered a marker of short-term mortality. The current research emphasizes the circumstances of the incidence and complications of the no-reflow phenomenon in STEMI patients, including in-hospital mortality. In this case-control study, conducted over two and a half years, there were enrolled 656 patients diagnosed with STEMI and reperfused through PPCI. Several patients (n = 96) developed an interventional type of no-reflow phenomenon. One third of the patients with a no-reflow phenomenon suffered complications during admission, and 14 succumbed. Regarding complications, the majority consisted of arrhythmias (21.68%) and cardiogenic shock (16.67%). The anterior localization of STEMI and the left anterior descending artery (LAD) as a culprit lesion were associated with the highest number of complications during hospitalization. At the same time, the time interval >12 h from the onset of the typical symptoms of myocardial infarction (MI) until revascularization, as well as multiple stents implantations during PPCI, correlated with an increased incidence of short-term complications. The no-reflow phenomenon in patients with STEMI was associated with an unfavorable short-term prognosis.
Keyphrases
- percutaneous coronary intervention
- st elevation myocardial infarction
- end stage renal disease
- newly diagnosed
- ejection fraction
- risk factors
- st segment elevation myocardial infarction
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- emergency department
- coronary artery disease
- acute myocardial infarction
- patient reported outcomes
- physical activity
- intensive care unit
- left ventricular
- depressive symptoms
- antiplatelet therapy
- coronary artery bypass grafting
- hepatitis b virus
- acute respiratory distress syndrome
- liver failure
- respiratory failure
- drug induced
- coronary artery bypass
- mechanical ventilation