Induction of Interferon-γ and Tissue Inflammation by Overexpression of Eosinophil Cationic Protein in T Cells and Exosomes.

Huai-Chia ChuangMing-Han ChenYi Ming ChenYi-Ru CiouChia-Hsin HsuehChing-Yi TsaiTse-Hua Tan

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2021)

Our findings indicate that ECP overexpression in T cells or T cell-derived exosomes may be a biomarker and pathogenic factor for nephritis, hepatitis, and arthritis associated with SLE.

Keyphrases

mesenchymal stem cells
cell proliferation
stem cells
systemic lupus erythematosus
transcription factor
rheumatoid arthritis
oxidative stress
disease activity
dendritic cells
amino acid
binding protein