Sex-specific and polygenic effects underlying resting heart rate and associated risk of cardiovascular disease.
Ada N NordeidetMarie KlevjerKarsten ØvretveitErik MadssenUlrik WisløffBen Michael BrumptonAnja ByePublished in: European journal of preventive cardiology (2024)
Our findings provide insight into the pleiotropic effects of the RHR variants, contributing towards an improved understanding of mechanisms linking RHR and disease. In addition, the sex-specific results might contribute to a more refined understanding of RHR as a risk factor for the different diseases.