Development of Dual Functional Nucleic Acid Delivery Nanosystem for DNA Induced Silencing of Bcl-2 Oncogene.

Somayeh KarimiMohamad Hassan FouaniAhmad Moshaii Maryam NikkhahSaman HosseinkhaniReza Sheikhnejad

Published in: International journal of nanomedicine (2020)

Remarkable photothermal properties of DNAi-conjugated 42 nm Au-NPs in parallel with their high cell internalization and cytotoxic effects introduce them as potential dual functional anticancer nanosystems.

Keyphrases

nucleic acid
photodynamic therapy
single cell
high glucose
cell therapy
diabetic rats
single molecule
sensitive detection
drug delivery
oxidative stress
climate change
gold nanoparticles
human health
mesenchymal stem cells