High numbers of myeloid derived suppressor cells in peripheral blood and ascitic fluid of cirrhotic and HCC patients.

Nadia ElwanMohamed Labib SalemAbdelrahman KobtanFerial El-KallaLoai MansourMohamed YousefAshraf Al-SabbaghAbdel-Aziz A ZidanSherief Abd-Elsalam

Published in: Immunological investigations (2017)

A high frequency of MDSCs was detected in the peripheral blood of cirrhotic and HCC patients, indicating presence of immunosuppressive arms. These cells could be targeted to develop a new effective immunotherapy or an adjuvant to current therapies.

Keyphrases

peripheral blood
high frequency
end stage renal disease
ejection fraction
induced apoptosis
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
cell cycle arrest
early stage
transcranial magnetic stimulation
endoplasmic reticulum stress
cell death
cancer therapy