Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts.

Elizabeth R VolkmannAnna-Maria Hoffmann-VoldYu-Ling ChangJonathan Patrick JacobsKirsten TillischEmeran A MayerPhilip J ClementsJohannes Roksund HovMartin KummenØyvind MidtvedtVenu LagishettyLin ChangJennifer S LabusØyvind MolbergJonathan Braun

Published in: BMJ open gastroenterology (2017)

The present analysis detected specific aberrations in the lower GIT microbiota of patients with SSc from 2 geographically and ethnically distinct cohorts. These findings suggest that GIT dysbiosis may be a pathological feature of the SSc disease state.

Keyphrases

systemic sclerosis
interstitial lung disease
machine learning
deep learning
copy number
gene expression
rheumatoid arthritis
dna methylation