Green Tea Catechins Decrease Solubility of Raloxifene In Vitro and Its Systemic Exposure in Mice.

Victoria O OyannaBaron J BechtoldKatherine D LynchM Ridge CallTyler N GrafNicholas H OberliesJohn D Clarke

Published in: Pharmaceutical research (2024)

This study demonstrated flavan-3-gallate catechins may decrease solubility of poorly water-soluble drugs such as raloxifene, particularly in the fasted state.

Keyphrases

water soluble
type diabetes
metabolic syndrome
drug induced
skeletal muscle