Serum autotaxin levels correlate with the severity of pruritus in intrahepatic cholestasis of pregnancy.

Sema Süzen Çaypınar Suleyman Cemil Oglak Mustafa Behram Zeynep Gedik Özköse Salim Sezer Sema Karakas

Published in: The journal of obstetrics and gynaecology research (2022)

Maternal serum ATX levels were significantly increased in ICP patients as compared with healthy pregnant women. Also, serum ATX activity was highly correlated with the itch intensity. We consider that ATX might represent a robust, accurate, and reliable circulating biomarker to diagnose ICP.

Keyphrases

pregnant women
end stage renal disease
pregnancy outcomes
ejection fraction
chronic kidney disease
prognostic factors
preterm birth
physical activity
birth weight
mass spectrometry
body mass index
patient reported outcomes
weight loss