Pancreatic beta-cell function dynamics in youth with GCK, HNF1A, and KCNJ11 genes mutations during mixed meal tolerance test.

Ingrida StankuteRimante DobrovolskieneEvalda DanyteRasa SteponaviciuteValerie M SchwitzgebelRasa Verkauskiene

Published in: Pediatric diabetes (2022)

In short-term perspective, GCK diabetes group revealed no deterioration of beta-cell function. Individualized treatment in monogenic diabetes showed improved beta-cell function.

Keyphrases

type diabetes
cardiovascular disease
glycemic control
mental health
physical activity
young adults
genome wide
metabolic syndrome
immune response
insulin resistance
combination therapy
weight loss
nuclear factor
smoking cessation