HLA and killer cell immunoglobulin-like receptor (KIRs) genotyping in patients with acute ischemic stroke.
Antonino TuttolomondoDomenico Di RaimondoRosaria PecoraroAlessandra CasuccioDanilo Di BonaAnna AielloGiulia AccardiValentina ArnaoGiuseppe ClementeVittoriano Della CorteCarlo MaidaIrene SimonettaCalogero CarusoRosario SquatritoAntonio Pintonull nullPublished in: Journal of neuroinflammation (2019)
Our findings of a higher frequency of activating KIR genes seem to be consistent with findings previously reported patients with coronary syndrome. This higher frequency of "proinflammatory" genes in subjects with ischemic stroke could also explain the immunoinflammatory activation of the acute phase of stroke.
Keyphrases
- acute ischemic stroke
- genome wide
- atrial fibrillation
- bioinformatics analysis
- genome wide identification
- coronary artery disease
- coronary artery
- single cell
- dna methylation
- signaling pathway
- high throughput
- cell therapy
- case report
- heart failure
- stem cells
- transcatheter aortic valve replacement
- bone marrow
- binding protein