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Brain connectivity correlates of cognitive dispersion in a healthy middle-aged population: influence of subjective cognitive complaints.

Lídia Mulet-PonsCristina Solé-PadullésMaría Cabello-ToscanoKilian Abellaneda-PérezRuben Perellón-AlfonsoGabriele CattaneoJavier Solana SánchezVanessa Alviarez-SchulzeNuria BargallóJosep Ma Tormos-MuñozAlvaro Pascual-LeoneDavid Bartrés-FazLídia Vaqué-Alcázar
Published in: The journals of gerontology. Series B, Psychological sciences and social sciences (2023)
In healthy middle-aged individuals, high cognitive dispersion was related to poorer cognition and DMN dysregulation, being these associations stronger amongst subjects with high SCC. Present results reinforce the interest in considering dispersion measures within neuropsychological evaluations, as they may be more sensitive to incipient age-related cognitive and functional brain changes than traditional measures of performance.
Keyphrases
  • middle aged
  • white matter
  • resting state
  • multiple sclerosis
  • cerebral ischemia
  • brain injury
  • subarachnoid hemorrhage