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Protective Effect of Mitophagy Regulated by mTOR Signaling Pathway in Liver Fibrosis Associated with Selenium.

Lichun QiaoZiwei GuoHaobiao LiuJiaxin LiuXue LinHuan DengXuan LiuYan ZhaoXiang XiaoJian LeiJing Han
Published in: Nutrients (2022)
Mitophagy regulated by the mTOR signaling pathway plays a dual protective role on low-selenium inducing liver fibrosis and nano-selenium supplements preventing liver fibrosis. Mitochondrial energy metabolism plays an important role in these processes as well.
Keyphrases
  • liver fibrosis
  • signaling pathway
  • pi k akt
  • cell proliferation
  • epithelial mesenchymal transition
  • oxidative stress
  • induced apoptosis
  • nlrp inflammasome
  • endoplasmic reticulum stress