DR10601, a novel recombinant long-acting dual glucagon-like peptide-1 and glucagon receptor agonist for the treatment of obesity and type 2 diabetes mellitus.
W WangX WenW DuanX WangY ChenJ DongZ YangJ FangZ ZhouG YaoY FangYanshan HuangPublished in: Journal of endocrinological investigation (2019)
Repeated administration of DR1060 provides potent and sustained glycemic control and body weight loss effect in high-fat DIO mice. DR10601 is a promising long-acting agent deserving further investigation for the treatment of type 2 diabetes and obesity.