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Haptoglobin 1-1 phenotype: A risk factor for 24-hours polyuria.

Upeksha Sewwandi AlwisSaskia RoggemanThomas F MonaghanMarie-Astrid DenysKarel EveraertJoris Delanghe
Published in: International journal of clinical practice (2019)
The Hp1 allele was more frequent in subjects with polyuria, and participants with the Hp 1-1 phenotype were at greater risk for polyuria. Hp 1-1 subjects demonstrated an altered ability to concentrate urine with a slower continuous excretion of sodium throughout the day. Plasma Hp concentration of Hp 1-1 was positively correlated with 24-hours sodium clearance in subjects without polyuria.
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