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Silk fibroin nanoparticles as biocompatible nanocarriers of a novel light-responsive CO-prodrug.

Ignacio Jiménez-AmezcuaFrancisco J CarmonaIgnacio Romero-GarcíaMiguel QuirósJosé L CenisAntonio Abel Lozano-PérezCarmen R MaldonadoElisa Barea
Published in: Dalton transactions (Cambridge, England : 2003) (2018)
[Mn(CO)3(2,2'-bipyridine)(PPh3)](ClO4) (1), a novel photoactive CO-releasing molecule, has been prepared and fully characterized. Besides, silk fibroin nanoparticles (SFNs) have been used, for the first time, as vehicles of 1 leading to the hybrid material 1@SFNs that shows an enhanced CO-delivery.
Keyphrases
  • tissue engineering
  • cancer therapy
  • drug release
  • drug delivery
  • wound healing
  • ionic liquid
  • bone regeneration
  • metal organic framework