Login / Signup

Real-world data on ALK rearrangement test in Chinese advanced non-small cell lung cancer (RATICAL): a nationwide multicenter retrospective study.

Lin LiWencai LiChunyan WuYanfeng XiLei GuoYuan JiLili JiangJi LiJingping YunGang ChenYuan LiYueping LiuDianbin MuYuchen HanLeina SunQingxin XiaXiaodong TengNan-Ying CheWei WuXueshan QiuChao LiuXiaochu YanDaiqiang LiZhi-Hong ZhangZhe WangYujun LiZheng WangLingchuan GuoXiu NieJingshu GengJianhua ZhouJianming Ying
Published in: Cancer communications (London, England) (2024)
This study highlights the real-world variability and challenges of ALK test in advanced NSCLC, demonstrating a predominant use of IHC-VENTANA-D5F3 with high consistency and distinct clinicopathological features in ALK-positive patients. These findings underscore the need for a consensus on optimal test practices and support the development of refined ALK test strategies to enhance diagnostic accuracy and therapeutic decision-making in NSCLC.
Keyphrases