Major bleeding during oral anticoagulant therapy associated with factor V activation by factor Xa.
Anja MaagNienke van ReinTim J SchuijtWil F KopatzDanielle KruijswijkStella ThomassenTilman M HackengRodney M CamireTom van der PollJoost C M MeijersMettine H A BosCornelis van 't VeerPublished in: Journal of thrombosis and haemostasis : JTH (2021)
A greater dependence on FXa-mediated activation of FV of TG is associated with increased risk of major bleeding during VKA therapy.