Front-Line Window Therapy with Temozolomide and Irinotecan in Patients with Primary Disseminated Multifocal Ewing Sarcoma: Results of the ISG/AIEOP EW-2 Study.
Sebastian Dorin AsafteiNadia PumaAnna PaioliMarco PetrazCarlo MorosiMarta Giorgia PoddaAngela TamburiniEmanuela PalmeriniLuca CoccoliGiovanni GrignaniCarla ManzittiRossella BertulliFrancesco De LeonardisMarco RabusinAnna CampelloElisa TirteiPiero PicciArcangelo PreteAlessandra LonghiFranca FagioliRoberto LukschPublished in: Cancers (2021)
the smooth handling and encouraging activity demonstrated by up-front TEMIRI did not change the EFS in PDMES, so this result suggests the need for the further evaluation of the efficacy of TEMIRI in combination with conventional treatments in non-metastatic patients.