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FLOT1 promotes tumor development, induces epithelial-mesenchymal transition, and modulates the cell cycle by regulating the Erk/Akt signaling pathway in lung adenocarcinoma.

Louqian ZhangYuan MaoQixing MaoWeifei FanLi XuYan ChenLin XuJun Wang
Published in: Thoracic cancer (2019)
The findings indicate a significant role of FLOT1 in LUAD development. Targeting FLOT1 may be a potential therapeutic strategy for LUAD.
Keyphrases
  • signaling pathway
  • cell cycle
  • epithelial mesenchymal transition
  • cell proliferation
  • pi k akt
  • induced apoptosis
  • transforming growth factor
  • drug delivery