Underdiagnosing of antibody-mediated transfusion-related acute lung injury: evaluation of cellular-based versus bead-based techniques.
D van SteinE A M BeckersA L PetersL PorcelijnRutger A MiddelburgN M LardyD J van RhenenA P J VlaarPublished in: Vox sanguinis (2016)
Bead-based techniques show a higher sensitivity for detecting incompatible donors in TRALI cases than cellular-based assays. These results suggest that the use of bead-based assays will result in a significant reduction of future TRALI reactions as more antibody positive donors will be excluded from future donations.