Disease extent and anti-tubercular treatment response correlates with Mycobacterium tuberculosis-specific CD4 T-cell phenotype regardless of HIV-1 status.

Catherine RiouElsa Du BruynSheena RuziveRene T GoliathCecilia S Lindestam ArlehamnAlessandro SetteAlan SherDaniel L BarberRobert J Wilkinson

Published in: Clinical & translational immunology (2020)

Whole blood-based assays of Mtb-specific CD4 T-cell activation and maturation markers can be used as non-sputum-based biomarkers of disease extent and treatment monitoring in TB, regardless of HIV-1 status.

Keyphrases

mycobacterium tuberculosis
antiretroviral therapy
pulmonary tuberculosis
hiv positive
hiv infected
hiv testing
human immunodeficiency virus
hepatitis c virus
hiv aids
men who have sex with men
high throughput