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Diagnostic, prognostic, and predictive importance of neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and CA125 in endometrial hyperplasia and carcinoma.

Bharti KumariDebaditya HaldarGuddi R SinghSweta KumariSangeeta PankajRajnikant Prasad
Published in: Indian journal of pathology & microbiology (2024)
NLR, PLR, and CA125 were marginally increased or normal in the case of endometrial hyperplasia without atypia and endometrial atypical hyperplasia, while they were significantly increased in endometrial carcinoma, and also correlated with an increase in grade, pT-stage, and nodal stage. Hence, these can be considered for additional screening as diagnostic, prognostic, and predictive markers in case of abnormal uterine bleeding with endometrial pathology.
Keyphrases
  • endometrial cancer
  • peripheral blood
  • neoadjuvant chemotherapy
  • locally advanced