Sedentary behaviour and physical activity are associated with biomarkers of endothelial dysfunction and low-grade inflammation-relevance for (pre)diabetes: The Maastricht Study.
Evelien J VandercappellenAnnemarie KosterHans H C M SavelbergSimone J P M EussenPieter C DagnelieNicolaas C SchaperMiranda T SchramCarla J H van der KallenMarleen M J van GreevenbroekAnke WesseliusMiranda T SchramAbraham A KroonRonald M A HenryCoen D A StehouwerPublished in: Diabetologia (2022)
Physical activity and sedentary behaviour are associated with biomarkers of endothelial dysfunction and low-grade inflammation. For biomarkers of endothelial dysfunction, associations between physical activity and sedentary behaviour were consistently stronger in (pre)diabetes than in normal glucose metabolism. Whether increasing physical activity or decreasing sedentary time can positively influence biomarkers of endothelial dysfunction in individuals with prediabetes and type 2 diabetes requires further study.