Axonal swellings are related to type 2 diabetes, but not to distal diabetic sensorimotor polyneuropathy.
Páll KarlssonSandra S GylfadottirAlexander G KristensenJuan D RamirezPedro CruzNhu LePallai R ShilloSolomon TesfayeAndrew S C RiceHatice TankisiNanna B FinnerupJens R NyengaardTroels S JensenDavid L H BennettAndreas C ThemistocleousPublished in: Diabetologia (2021)
In individuals with type 2 diabetes where IENFD is >1.0 fibre/mm, axonal swelling ratio is related to type 2 diabetes but is not related to DSP or painful DSP. Axonal swellings may be an early marker of sensory nerve injury in type 2 diabetes.