The effects of the standardized extracts of Ginkgo biloba on steroidogenesis pathways and aromatase activity in H295R human adrenocortical carcinoma cells.

Mijie Kim Yong Joo Park Huiyeon Ahn Byeonghak Moon Kyu Hyuck Chung Seung Min Oh

Published in: Environmental health and toxicology (2016)

These results suggest that EGb761 could regulate steroidogenesis-related genes such as CYP19 and 17β-HSD1, and lead to a decrease in 17β-estradiol and testosterone. The present study provides good information on potential therapeutic effects of EGb761 on estrogen dependent breast cancer.

Keyphrases

endothelial cells
estrogen receptor
induced pluripotent stem cells
replacement therapy
risk assessment
health information
human health