Transdiagnostic dimensions of psychopathology at first episode psychosis: findings from the multinational EU-GEI study.
Diego QuattroneMarta Di FortiCharlotte Gayer-AndersonLaura FerraroHannah E JongsmaGiada TripoliCaterina La CasciaDaniele La BarberaIlaria TarriconeDomenico BerardiAndrei SzökeCelso ArangoAntonio LasalviaAndrea TortelliPierre-Michel LlorcaLieuwe de HaanEva VelthorstJulio BobesMiguel BernardoJulio SanjuánJose Luis SantosManuel ArrojoCristina Marta Del-BenPaulo Rossi MenezesJean-Paul Seltennull nullPeter B JonesJames B KirkbrideAlexander L RichardsMichael C O'DonovanPak C ShamEvangelos VassosBart Pf RuttenJim van OsCraig MorganCathryn M LewisRobin M MurrayUlrich ReininghausPublished in: Psychological medicine (2018)
Our results suggest that the bifactor model of psychopathology holds across diagnostic categories of non-affective and affective psychosis at FEP, and demographic and context determinants map onto general and specific symptom dimensions. These findings have implications for tailoring symptom-specific treatments and inform research into the mood-psychosis spectrum.