Educational disparities in brain health and dementia across Latin America and the United States.
Raúl González-GómezAgustina LegazSebastián MoguilnerJosephine CruzatHernán HernándezSandra BaezRafael CocchiCarlos Coronel-OliveroVicente MedelEnzo TagliazuchiJoaquín MigeotCarolina Ochoa-RosalesMarcelo Adrián MaitoPablo ReyesHernando Santamaria GarciaMaria E GodoyShireen JavandelAdolfo M GarcíaDiana L MatallanaJosé Alberto Avila-FunesAndrea SlachevskyMaría I BehrensNilton CustodioJuan F CardonaIgnacio L BruscoMartín A BrunoAna L Sosa OrtizStefanie D Pina-EscuderoLeonel T TakadaElisa de Paula França ResendeVictor ValcourKatherine L PossinMaira Okada de OliveiraFrancisco LoperaBrian LawlorKun HuBruce MillerJennifer S YokoyamaCecilia Gonzalez CampoAgustin M IbanezPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)
Lower education was linked to reduced brain volume and connectivity in healthy controls (HCs), Alzheimer's disease (AD), and frontotemporal lobar degeneration (FTLD). Latin American cohorts have lower educational levels compared to the those in the United States. Educational disparities majorly drive brain health differences between regions. Educational differences were significant in both conditions, but more in AD than FTLD. Education stands as a critical factor in classifying aging and dementia across regions.