Scriptaid enhances skeletal muscle insulin action and cardiac function in obese mice.

Vidhi GaurTimothy ConnorKylie VenardosDarren C HenstridgeSheree D MartinCourtney SwintonShona MorrisonKathryn Aston-MourneyStefan M GehrigRoelof van EwijkGordon S LynchMark A FebbraioGregory R SteinbergMark HargreavesKen R WalderSean L McGee

Published in: Diabetes, obesity & metabolism (2017)

These data show that pharmacological targeting of the class IIa HDAC corepressor complex with Scriptaid could be used to enhance muscle insulin action and cardiac function in obesity.

Keyphrases

skeletal muscle
type diabetes
insulin resistance
glycemic control
metabolic syndrome
weight loss
electronic health record
cancer therapy
weight gain
adipose tissue
big data
machine learning