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Semaglutide (SUSTAIN and PIONEER) reduces cardiovascular events in type 2 diabetes across varying cardiovascular risk.

Mansoor HusainStephen C BainOle K JeppesenIldiko LingvayRasmus SørrigMarianne B TreppendahlTina Vilsbøll
Published in: Diabetes, obesity & metabolism (2020)
In SUSTAIN and PIONEER combined, glucagon-like peptide-1 analogue semaglutide showed consistent effects on MACE versus comparators across varying CV risk. No effect of semaglutide on MACE was observed in subjects with prior HF.
Keyphrases
  • cardiovascular events
  • type diabetes
  • cardiovascular disease
  • coronary artery disease
  • glycemic control
  • heart failure
  • acute heart failure
  • metabolic syndrome