The effects of altered DNA damage repair genes on mutational processes and immune cell infiltration in esophageal squamous cell carcinoma.
Huangbo YuanTao QingSibo ZhuXiaorong YangWeicheng WuKelin XuHui ChenYanfeng JiangChengkai ZhuZiyu YuanTiejun ZhangLi JinChen SuoMing LuXingdong ChenWeimin YePublished in: Cancer medicine (2023)
This research demonstrated that DDR alterations could impact mutational processes and immune cell infiltration in ESCC. The suppression of HFM1 and NEIL1 could play a crucial role in ESCC progression and may also serve as prognostic markers.