Rituximab-Containing Risk-Adapted Treatment Strategy in Nodular Lymphocyte Predominant Hodgkin Lymphoma: 7-Years Follow-Up.
Novella PuglieseMarco PicardiRoberta Della PepaClaudia GiordanoFrancesco MurianoAldo LeoneGiuseppe Delle CaveAlessandro D'AmbrosioVioletta MarafiotiMaria Gabriella RascatoDaniela RussoMassimo MascoloFabrizio PanePublished in: Cancers (2021)
Our results confirm the value of Rituximab in NLPHL therapy and show that Rituximab (single-agent) induction and maintenance in a limited-stage, or Rituximab with ABVD only in the presence of risk factors, give excellent results while sparing cytotoxic agent- and/or RT-related damage. Furthermore, Rituximab inclusion in advanced-stage therapeutic strategy seems to improve PFS compared to conventional chemo-radiotherapy.
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