Circulating MicroRNAs as Predictors of Beta Cell Function in Youth-Onset Type 2 Diabetes: The TODAY study.

Dakota RedlingShannon BialakLaure El Ghormli Steven D ChernausekKenneth JonesJeanie B Tryggestad

Published in: The Journal of clinical endocrinology and metabolism (2024)

The miRNA species associated with beta cell function are associated with alterations in cellular metabolism and apoptosis, suggesting that differences in baseline abundance may serve as circulating markers of beta cell dysfunction and provide potential mechanistic insights into the aggressive nature of youth-onset type 2 diabetes.

Keyphrases

type diabetes
oxidative stress
physical activity
mental health
glycemic control
young adults
cardiovascular disease
single cell
insulin resistance
endoplasmic reticulum stress
cell death
cell therapy
cell cycle arrest
mesenchymal stem cells
pi k akt
anaerobic digestion